RIFAMPICIN KIMIA FARMA 600 MG KAPLET Kegunaan, Efek Samping, Dosis dan Aturan Pakai
The optimal dosing strategy for rifampicin in treating drug-susceptible tuberculosis (TB) is still highly debated. In the Phase 3 clinical trial Study 31/ACTG 5349 (NCT02410772), all participants in the control regimen arm received 600 mg rifampicin daily as a flat dose.
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View rifampicin information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding,. 600-900 mg 3 times a week for 6 months (initial and continuation phases). Tuberculosis, in combination with other drugs (standard unsupervised 6-month treatment) for rifampicin
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Following a single 600 mg oral dose of rifampin in healthy adults, the peak serum concentration averages 7 mcg/mL but may vary from 4 to 32 mcg/mL. Absorption of rifampin is reduced by about 30% when the drug is ingested with food. Rifampin is widely distributed throughout the body. It is present in effective concentrations in many organs and.
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Rifampin is a semisynthetic antibiotic used to treat latent or active tuberculosis, a disease caused by mycobacterial infection, and the asymptomatic carrier state of meningococcal disease. Common side effects of rifampin include heartburn, abdominal distress, nausea, vomiting, gas (flatulence), abdominal cramps, diarrhea, loss of appetite (anorexia), elevated liver enzymes, and mild itching.
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Belching. bloated or full feeling. excess air or gas in the stomach or bowels. indigestion. not able to concentrate. pain or discomfort in the chest, upper stomach, or throat. tooth discoloration. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
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The 600-mg once daily dose of rifampicin plays a key role in tuberculosis treatment. The evidence underpinning this dose is scant. A review of the historical literature identified 3 strands of reasoning. The first is the pharmacokinetic argument: The 600-mg dose yields serum drug concentrations well above the minimum inhibitory concentration of.
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Side Effects. Upset stomach, heartburn, nausea, or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. This medication may cause urine, sweat.
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the usual daily dose is 600 mg. A single dose of 600 mg once a month may be given. Children For paucibacillary forms, Rifampicin should be administered with dapsone for a period of 6 months. For multibacillary forms, Rifampicin should be administered with dapsone and clofazimine for a period of 12 months. The recommended dose is:
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This medication is used to prevent and treat tuberculosis and other bacterial infections. Rifampin belongs to a class of drugs known as rifamycin antibiotics. It works by stopping the growth of.
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For oral dosage form (capsules): For the treatment of meningitis bacteria in the nose or throat: Adults—600 milligrams (mg) 2 times a day for 2 days. Children 1 month of age and older—Dose is based on body weight and must be determined by your doctor. The dose is 10 mg per kilogram (kg) of body weight every 12 hours for 2 days.
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Patients on regimens of >600 mg once or twice weekly may experience adverse reactions, including flulike syndrome. History of diabetes mellitus (rifampin may make diabetes management more difficult) Regimens of >600 mg once or twice weekly may cause leukemia, anemia, or thrombocytopenia.
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In small-scale studies, high doses (20 mg/kg) of rifampicin have already been shown to have bactericidal activity up to twice that of the 600-mg dose (10 mg/kg) [40, 46]. Moreover, rifampicin has a sterilizing effect—the capacity to kill the remaining mycobacteria that undergo sporadic metabolism and that remain after the initial phase of.
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Rifampicin (150 MG) + Ethambutol hydrochloride (275 MG) + Isoniazid (400 MG) + Pyrazinamide (75 MG) Tablet, film coated: Oral: องค์การเภสัชกรรม: 2008-05-19: Not applicable: Thailand: แลพโปรมิกซ์: Rifampicin (600 MG) + Dapsone (100 MG) Kit: บริษัท พอนด์ เคมี.
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Once-daily therapy: 10 mg/kg/day once daily (usual dose: 600 mg). Note: The preferred frequency of administration is once daily during the intensive and continuation phases; however, 5-days-per-week administration by directly observed therapy (DOT) is an acceptable alternative.
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Rifampin dosage not to exceed 600 mg/day; Pediatric Dosage: 10-20 mg/kg/day intravenously/orally or 10-20 mg/kg orally twice-weekly (DOT); not to exceed 600 mg/day; Neisseria meningitidis Carrier. Adult Dosage. 600 mg every 12 hours for 2 days; Pediatric Dosage. Prophylaxis. Infants 1 month and younger: 10 mg/kg/day orally divided every 12.
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Rifampin for injection USP contains rifampin 600 mg, sodium formaldehyde sulfoxylate dihydrate 10 mg, and sodium hydroxide to adjust pH. Rifampin for injection is a sterile, lyophilized powder for intravenous infusion only.. (C3Hf/DP) mice dosed for 60 weeks with rifampicin followed by an observation period of 46 weeks, at 20 to 120 mg/kg.